Grille, S.J., Bellacosa, A., Larue, L. R?gulation de la E-cadh?rine par la prot?ine Akt. Compte-rendu de la soci?t? de Biologie (in press).
Bellacosa, A., Testa, J.R., Moore, R., Larue, L. A portrait of AKT kinases: human cancer and animal models depict a family with strong individualities. Cancer Biol. Ther. 3:268-275, 2004.
Caluseriu, O., Di Gregorio, C., Lucci-Cordisco, E., Santarosa, M., Trojan, J., Brieger, A., Benatti, P., Pedroni, M., Colibazzi, T., Bellacosa, A., Neri, G., Ponz de Leon, M., Viel, A. Genuardi, M. A founder MLH1 mutation in families from the districts of Modena and Reggio-Emilia in northern Italy with hereditary non-polyposis colorectal cancer associated with protein elongation and instability. J. Med. Genet. 41:e34, 2004.
Cortellino, S., Turner, D.P., Albino, D. Bellacosa, A. Induction of DNA damage by alkylating agents. In Cell Cycle Control and Dysregulation Protocols, edited by A. Giordano and G. Romano. Humana Press Inc., Clifton, NJ, pp. 121-125, 2004.
Cortellino, S., Turner, D.P. Bellacosa, A. Induction of DNA damage by gamma irradiation. In Cell Cycle Control and Dysregulation Protocols, edited by A. Giordano and G. Romano. Humana Press Inc., Clifton, NJ, pp. 127-132, 2004.
Grille, S.J., Bellacosa, A., Larue, L. MTA3, a MI-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer (Fujita et al. Cell 113:207-219, 2003). (Commentary). The Women's Oncol. Rev. 4:13-15, 2004.
Grille, S.J., Moore, R., Denat, L., Morali, O.G., Delmas, V., Bellacosa, A., Larue, L. The role of insulin-like growth factors in the epithelial to mesenchymal transition. In Rise and Fall of the Epithelial Phenotype, edited by P. Savagner. Landes Biosciences, Georgetown, TX, pp. 215-235, 2004.
Stoyanova, R., Clapper, M.L., Bellacosa, A., Henske, E.P., Testa, J.R., Ross, E.A., Yeung, A.T., Nicolas, E., Tsichlis, N., Li, Y.-S., Linehan, W.M., Howard, S., Campbell, K.S., Godwin, A.K., Boman, B.M., Crowell, J.A., Kopelovich, L., Knudson, A.G. Altered gene expression patterns in phenotypically normal renal cells from individuals heterozygous for mutations in tumor suppressor genes. Cancer Biol. Ther. 3:1313-1321, 2004.
Stoyanova, R., Upson, J.J., Patriotis, C., Ross, E.A., Henske, E.P., Datta, K., Boman, B., Clapper, M.L., Knudson, A.G., Bellacosa, A. Use of RNA amplification in the optimal characterization of global gene expression using cDNA microarrays. J. Cell. Physiol. 201:359-365, 2004.
Turner, D.P., Yeung, A.T. Bellacosa, A. Induction of DNA damage by UV irradiation. In Cell Cycle Control and Dysregulation Protocols, edited by A. Giordano and G. Romano. Humana Press Inc., Clifton, NJ, pp. 133-137, 2004.
Upson, J.J., Stoyanova, R., Cooper, H.S., Patriotis, C., Ross, E.A., Boman, B., Clapper, M.L., Knudson, A.G., Bellacosa, A. Optimized procedures for microarray analysis of histological specimens processed by laser capture microdissection. J. Cell. Physiol. 201:366-373, 2004.
Bellacosa, A. Genetic hits and mutation rate in colorectal tumorigenesis: versatility of Knudson's theory and implications for cancer prevention. Genes Chromosomes Cancer 38:382-388, 2003.
Bellacosa, A., Moss, E.G. RNA repair: damage control. Curr. Biol. 13:R482-484, 2003.
Borgatti, P., Martelli, A.M., Tabellini, G., Bellacosa, A., Capitani, S., Neri, L.M. A threonine 308 phosphorylated form of Akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin. J. Cell. Physiol. 196:79-88, 2003.
Cortellino, S., Turner, D., Masciullo, V., Schepis, F., Albino, D., Daniel, R., Skalka, A.M., Meropol, N.J., Alberti, C., Larue, L., Bellacosa, A. The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity. Proc. Natl. Acad. Sci.USA 100:15071-15076, 2003.
Grille, S.J., Bellacosa, A., Upson, J.J., Klein-Szanto, A., van Roy, F., Donowitz, M., Tsichlis, P.N., Larue, L. The protein kinase Akt induces epithelial-mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res. 63:2172-2178, 2003.
Neri, L.M., Borgatti, P., Tazzari, P.L., Bortul, R., Cappellini, A., Tabellini, G., Bellacosa, A., Capitani, S., Martelli, A.M. The Phosphoinositide 3-Kinase/Akt Pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells. Molecular Cancer Res. 1:234-246, 2003.
Turner, D.P., Bellacosa, A. Insights into DNA recombination from the structure of a RAD51-BRCA2 complex (Pellegrini, et al. Nature 420:287-293, 2002). (Commentary). The Women's Oncology Review. 3:43-45, 2003.
Condorelli, G., Drusco, A., Stassi, G., Bellacosa, A., Roncarati, R., Iaccarino, G., Russo, M.A., Gu, Y., Dalton, N., Chung, C., Latronico, M.V., Napoli, C., Sadoshima, J., Croce, C.M., Ross, J., Jr. Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc. Natl. Acad. Sci. USA 99:12333-12338, 2002.
Viglietto, G., Motti, M.L., Bruni, P., Melillo, R.M., D'Alessio, A., Califano, D., Vinci, F., Chiappetta, G., Tsichlis, P.N., Bellacosa, A., Fusco, A., Santoro, M. Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by Akt-mediated phosphorylation in breast cancer. Nat. Med. 8:1136-1144, 2002.
Bellacosa, A. Functional interactions and signaling properties of mammalian DNA mismatch repair proteins. Cell Death Differ. 8:1076-92, 2001.
Bellacosa, A. Role of MED1 (MBD4) gene in DNA repair and human cancer. J. Cell. Physiol. 187:137-144, 2001.
Drummond, J.T., Bellacosa, A. Human DNA mismatch repair in vitro operates independently of methylation status at CpG sites. Nucl. Acids Res. 29:2234-43, 2001.
Fiumicino, S., Ercoli, A., Ferrandina, G., Hess, P., Raspaglio, G., Genuardi, M., Rovella, V., Bellacosa, A., Cicchillitti, L., Mancuso, S., Bignami, M., Scambia, G. Microsatellite instability is an independent indicator of recurrence in sporadic stage I-II endometrial adenocarcinoma. J. Clin. Oncol. 19:1008-1014, 2001.
Testa, J.R., Bellacosa, A. AKT plays a central role in tumorigenesis. Proc. Natl. Acad. Sci. USA 98:10983-10985, 2001.
Xiao, G. H., Jeffers, M., Bellacosa, A., Mitsuuchi, Y., Vande Woude, G. F., Testa, J.R. Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways. Proc. Natl. Acad. Sci. USA 98:247-252, 2001.