Zimei Bu, PhD

Associate Member
Basic Science Division


Zimei.Bu@fccc.edu
Phone: 215-728-7051



Recent Publications

2007

Li,J., Poulikakos, P.I., Dai, D., Testa, J.R., Callaway,D.J., and Bu, Z. PKC phosphorylation disrupts NHERF autoinhibition and promotes CFTR macromolecular assembly. J. Bio. Chem., 282:27086-27099, 2007

Dawson, J.B., Bu, Z., Lemmon, M.A. Ligand-induced structural transitions in ErbB receptor extracellular domains. Structure, 15:942-954, 2007

Bu Z, Shi Y, Callaway DJ, Tycko R. Free Full Text       Molecular alignment within {beta} sheets in Ab14-23 fibrils: solid state NMR experiments and theoretical predictions. Biophys. J. 92: 594-602, 2007


2006

Shi, Y., Stouten, P.F.W., Pillalamarri, N., Barile, L., Rosal, R.V., Teichberg, S., Bu, Z., Callaway, D.J. Quantitative determination of the topological propensities of amyloidogenic peptides. Biophys. Chem. 120:55-61, 2006.

Fang, M., Cheng, H., Dai, Z., Bu, Z., Sigal, L.J. Immunization with a single extracellular enveloped virus protein produced in bacteria provides partial protection from a lethal orthopoxvirus infection in a natural host. Virology 345:231-243, 2006.

2005


Li, J., Dai, Z., Jana, D., Callaway, D.J.E., Bu, Z. Ezrin controls the macromolecular complexes formed between an adaper protein Na+/H+ exchanger regulatory factor and the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 280:37634-37643, 2005.

Bu, Z., Biehl, R., Monkenbusch, M., Richter, D., Callaway, D.J. Coupled domain motion in Taq DNA polymerase revealed by neutron spin echo spectroscopy. Proc. Natl. Acad. Sci. U.S.A. 102:17646-17651, 2005.

2004


Ho, D.L., Byrnes, W.M., Ma, W.P., Shi, Y., Callaway D.J., Bu Z. Structure-specific DNA-induced conformational changes in Taq polymerase revealed by small angle neutron scattering. J. Biol. Chem. 279:39146-39154, 2004.

2003


Bu, Z., Wang, L., Kendall, D.A. Nucleotide binding induces changes in the oligomeric state and conformation of Sec A in a lipid environment: a small-angle neutron-scattering study. J. Mol. Biol. 332:23-30, 2003.

Laksanalamai, P., Jiemjit, A., Bu, Z., Maeder, D.L., Robb, F.T. Multi-subunit assembly of the Pyrococcus furiosus small heat shock protein is essential for cellular protection at high temperature. Extremophiles 7:79-83, 2003.