Jonathan D Cheng, MD

Associate Member
Medical Science Division


Jonathan.Cheng@fccc.edu
Phone: 215-728-2805
Fax: 215-728-3639
Jonathan D Cheng, MD


Recent Publications

In Press

Lai KS, Ho NH, Cheng JD, Tung CH. Selective fluorescence probes for dipeptidyl peptidase activity - fibroblast activation protein and dipeptidyl peptidase IV. Bioconjug Chem 2007 (in press).

Maes MB, Dubois V, Brandt I, Lambeir AM, VanderVeken P, Augustyns K, Cheng JD, Chen X, Scharpe S, DeMeester I. Dipeptidyl peptidase 8/9 like activity in human leukocytes. J Leuk Biol 2007 (in press).

Konski AA, Cheng JD, Goldberg M, Li T, Maurer A, Yu JQ, Haluszka O, Scott W, Meropol NJ, Cohen SJ, Freedman G, Weiner LM. Correlation of molecular response as measured by 18-FDG-PET with outcome after chemo-radiation in patients with esophageal carcinoma. Int J Radiat Oncol Biol Phys 2007 (in press)

2007

Henry LR, Sigurdson E, Ross EA, Lee JS, Watson JC, Cheng JD, Freedman GM, Konski A, Hoffman JP. Resection of isolated pelvic recurrences after colorectal surgery: Long-term results and predictors of improved clinical outcome. Ann Surg Oncol 14:1081-1091, 2007.

Henry LR, Lee HO, Lee JS, Klein-Szanto A, Watts P, Ross EA, Chen WT, Cheng JD. Clinical implications of fibroblast activation protein (FAP) in patients with colon cancer. Clin Cancer Res 2007 13: 1736-1741, 2007.

Freedman GM, Meropol NJ, Sigurdson ER, Hoffman J, Callahan E, Price R, Cheng J, Cohen S, Lewis N, Watkins-Bruner D, Rogatko A, Konski A. Phase I trial of preoperative hypofractionated intensity modulated radiation therapy (IMRT) with incorporated boost and oral capecitabine in locally advanced rectal cancer. Int J Radiat Oncol Biol Phys 67:1389-1393, 2007.


2006

Cohen SJ, Alpaugh RK, Gross S, O'Hara SM, Smirnov DA, Terstappen LW, Allard WJ, Bilbee M, Cheng JD, Hoffman JP, Lewis NL, Pellegrino A, Rogatko A, Sigurdson E, Wang H, Watson JC, Weiner LM, Meropol NJ. Isolation and Characterization of Circulating Tumor Cells in Patients with Metastatic Colorectal Cancer. Clin Colorectal Cancer 6:125-132, 2006.

2005

Pedri H, Wang H, Babb J, Miller SM, Movsas B, Sherman E, Ridge JA, Under M, Langer C, Goldberg M, Scott W, Cheng J.  A Randomized Pilot Study of Cognitive-Behavioral Therapy Versus Basic Health Education for Smoking Cessation Among Cancer Patients.  Ann Behav Med 30:1-11, 2005.

Henry LH, Goldberg M, Scott W, Konski A, Meropol NJ, Freedman G, Weiner L, Watts P, Beard M, McLaughlin S, Cheng JD. Induction cisplatin and paclitaxel followed by combination chemoradiotherapy with 5-FU, cisplatin, and paclitaxel prior to resection in localized esophageal cancer- a phase II report.  Ann Surg Oncol 13:1-7, 2005.

Konski A, Hoffman J, Sigurdson E, Haluszka O, Engstrom P, Cheng JD, Cohen SJ, Watson JC, Eisenberg D, McGarrity E, Freedman G, and Meropol NJ. Can Molecular Imaging Predict Response to Pre-operative Chemoradiation in Patients with Rectal Cancer? A
Fox Chase Cancer Center Prospective Experience.  Sem Oncol 32:S63-67, 2005

Berger AC, Scott WJ, Freedman G, Konski A, Weiner L, Cheng JD, Goldberg M. Morbidity and mortality are not increased after induction chemoradiotherapy followed by esophagectomy in patients with esophageal cancer. Semin Oncol. 32:S16-20, 2005.

Ang KK, Harris J, Garden AS, Trotti A, Jones CU, Carrascosa L, Cheng JD, Spencer SS, Forastiere A, and Weber RS. Concomitant Boost Radiation plus Concurrent Cisplatin for Advanced Head and Neck Carcinomas: A Phase II Trial of the Radiation Therapy Oncology Group (RTOG 99-14). J Clin Oncol 23:3008-3015, 2005.

Berger AC, Farma J, Scott WJ, Freedman G, Weiner L, Cheng JD, Wang H, Goldberg M. Complete Response to Neoadjuvant Chemoradiotherapy in Esophageal Carcinoma Is Associated With Significantly Improved Survival. J Clin Oncol. J Clin Oncol 23:4330-4337, 2005.

Cheng JD, Adams GP, Robinson MK, and Weiner LM. Monoclonal antibodies. In: Cancer: Principles and Practice of Oncology, 7th Ed. DeVita VT, Hellman S, Rosenberg SA, eds. Lippincott Williams & Wilkins 2005: 445-456.

Cheng JD, Valianou M, Canutescu AA, Jaffe EK, Lee H, Wang H, Lai JH, Bachovchin WW, and Weiner LM. Abrogation of Fibroblast Activation Protein Enzymatic Activity Attenuates Tumor Growth. Mol Cancer Ther 4:351-360, 2005

Kramer NM, Horwitz EM, Cheng J, Ridge JA, Feigenberg SJ, Cohen RB, Nicolaou N, Sherman EJ, Babb JS, Damsker JA, Langer CJ. Toxicity and outcome analysis of patients with recurrent head and neck cancer treated with hyperfractionated split-course reirradiation and concurrent cisplatin and paclitaxel chemotherapy from two prospective phase I and II studies. Head Neck 27:406-414, 2005.

2004

Cheng JD, Langer C, Aamdal S, Robert F, Engelhardt LR, Fernberg O, Schiller J, Forsberg G, Alpaugh RK, Weiner LM, Babb JS, and Andre Rogatko A. Individualized patient dosing in phase I clinical trials: The role of EWOC in PNU-214936. J Clin Oncol. 22:602-609, 2004.

Schnoll RA, Rothman RL, Lerman C, Miller SM, Newman H, Movsas B, Sherman E, Ridge JA, Unger M, Langer C, Goldberg M, Scott W, and Cheng J. Comparing cancer patients who enroll in a smoking cessation program at a comprehensive cancer Center with those who decline enrollment. Head Neck 26:278-286, 2004.

Schnoll RA, Rothman RL, Newman H, Lerman C, Miller SM, Movsas B, Sherman E, Ridge JA, Unger M, Langer C, Goldberg M, Scott W, and Cheng J. Characteristics of cancer patients entering a smoking cessation program and correlates of quit motivation. Psychooncology 13:346-358, 2004.

2003

Cheng JD and Weiner LM. Tumors and Their Microenvironments: Tilling the Soil. Clin Cancer Res 9:1639-1647, 2003.

2002

Cheng JD, Dunbrack RL, Vilianou M, Rogatko A, Alpaugh RK, and Weiner LM. Promotion of tumor Growth by murine fibroblast activation protein (FAP), a serine protease, in an Animal Model. Cancer Res 62:4767-4772, 2002