Edna Cukierman, PhD

Associate Member
Basic Science Division


Edna.Cukierman@fccc.edu
Phone: 215-214-4218
Fax: 215-728-3616


Recent Publications

In Press

Cukierman, E. Stromagenesis. In: Encyclopedia of Cancer (Schwab, M. ed.)  Heidelberg/Germany: Springer, In press, 2008.

 

Castelló-Cros, R., and Cukierman, E... Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices. In Methods Mol. Biol. / Extracellular Matrix Protocols. S. Even-Ram, editor. Humana Press, Totowa, NJ,. In press, 2008.

 

Damianova, R., Stefanova, N., Cukierman, E., Momchilova, A. and Pankov, R. Three-dimensional matrix induces sustained activation of ERK1/2 via Src/Ras/Raf signaling pathway. Cell Biol Int In press, 2007.

Cukierman, E.  Three-dimensional tumor-associated stromal system; preparation of extracellular matrices produced by immortalized and primary fibroblasts.  Chapter publication for the 2007 Summer School on Nanobiology of the Center for Functional Nanostructures. Bad Herrenalb, Germany. In press, 2007.

2007

 

Yamada, K.M., Cukierman, E. Modeling tissue morphogenesis and cancer in 3D.  Cell. 130:(August 24 issue), 2007.

 

2006

 

Beacham, D.A., Amatangelo, M.D., Cukierman, E.  Preparation of extracellular matrices produced by cultured and primary fibroblasts.  In: Current Protocols in Cell Biology (Bonifacino, J.S., Dasso, M., Lippincott-Schwartz, J., Harford, J.B., Yamada, K.M. eds.) pp. 10.9.1-10.9.21, John K. Wiley & Sons, New York, NY, 2006.

 

2005

Cukierman, E.  Tumour development due to stroma permissiveness.  J. Biosci.  30:551-552, 2005.

Pankov R., Endo Y., Even-Ram S., Araki M., Clark K., Cukierman E., Matsumoto K., and Yamada K.M., A Rac switch regulates random versus directionally persistent cell migration. J. Cell Biol. 170:173-802, 2005.

 

Amatangelo, M.D., Bassi, D.E., Klein-Szanto, A.J., Cukierman, E., Stroma-derived 3D matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts. Am. J. Pathol. 167:475-488, 2005.

Beacham, D.A., Cukierman, E. Stromagenesis: The changing face of fibroblastic microenvironments during tumor progression. Semin. Cancer Biol. 15:329-341, 2005.

Bassi, DE., Lopez DeCicco, R., Cenna, J., Litwin, S., Cukierman, E., Klein-Szanto, AJ. PACE4 expression in mouse basal keratinocytes results in basement membrane disruption and acceleration of tumor progression. Cancer Res. 65:7310-9,005

Johnson, J.E., Varkonyi, R.J., Schwalm, J., Cragle, R., Klein-Szanto, A., Patchefsky, A., Cukierman, E., von Mehren, M., Broccoli, D. Multiple mechanisms of telomere maintenance exist in liposarcomas. Clin Can Res, 11:5347-5355, 2005.

2004

Cukierman, E. Cell migration analyses within fibroblast-derived 3D matrices. In: Cell Migration in Development. (Guan, J., ed.) Methods in Molecular Biology. Humana Press, Totowa, NJ, 2004.

Einarson, M.B., Cukierman, E., Compton, D.A., and Golemis, E.A. Human Enhancer of Invasion-Cluster, a coiled-coil protein required for passage through mitosis. Mol Cell Biol. 24: 3957-3971, 2004.

Cukierman, E. A visual-quantitative analysis of fibroblastic stromagenesis in breast cancer progression. J. Mammary Gland Biol. Neoplasia 9:311-324, 2004.

2003

Yamada, K.M., Pankov, R., Cukierman, E. Dimensions and dynamics in integrin function. Brazilian J. Med. Biol. Res. 36: 959-966, 2003.

Katz, B.-Z., Romer, L., Miyamoto, S., Volberg, T., Matsumoto K., Cukierman, E., Geiger, B., and Yamada, K. M. Targeting membrane-localized FAK to focal adhesions: Roles of tyrosine phosphorylation and Src family kinases. J. Biol. Chem. 278: 29115-29120, 2003.

Zajaczkowski, M.B., Cukierman, E., Galbraith, C.G., Yamada, K.M. Cell-Matrix Adhesions on PVA Hydrogels. Tissue Eng. 9: 525-33, 2003.

Pankov, R., Cukierman, E., Clark, K., Matsumoto, K., Hahn, C., LaFlamme, S. E., Poulin, B., and Yamada, K. M. Specific Beta-1 integrin site selectively regulates Akt/PKB signaling via local activation of PP2A. J. Biol. Chem. 278: 18671-18681, 2003.

Engelholm, L. H., List, K., Netzel Arnett, S., Cukierman, E., Mitola, D.J., Aaronson, H., Kj?ller, L., J?rgen K. L., Yamada, K. M., Strickland, D. K., Holmback, K., Dan?, K., Birkedal-Hansen, H., Behrendt, N., and Bugge, T. H. uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion. J. Biol. Chem. 278: 18671-18681, 2003.

2002

Aframian, D. J., Tran, S. D., Cukierman, E., Yamada, K. M., and Baum, B. J. Absence of tight junction formation in an allogeneic graft cell line used for developing an artificial salivary gland. Tissue Eng. 8: 871-878, 2002.

Aframian, D. J., Redman, R. S., Yamano, S., Nikolovski, J., Cukierman, E., Yamada, K. M., Kriete, M. F., Swaim, W. D., Mooney, D. J., and Baum, B. J. Tissue compatibility of two biodegradable tubular scaffolds implanted beneath the skin of buccal mucosa in mice. Tissue Eng. 8: 649-659, 2002.

Cukierman, E., Pankov, R., and Yamada, K. M. Cell interactions with 3D matrices. Curr. Opin. in Cell Boil. 14: 633-640, 2002.

Cukierman, E. Preparation of extracellular matrices produced by cultured fibroblasts. Curr. Protocols Cell Biol. 10.9.1-10.9.14, John K. Wiley & Sons, 2002.

Huber, I., Cukierman, E., Rotman, M., Cassel, D. ARF GTPase-activating protein 1. Methods Mol. Biol. 189: 199-206, 2002.

Selected Publications Prior to 2002

Cukierman, E., Pankov, R., Stevens, D. R., and Yamada, K. M. Taking cell-matrix adhesions to the third dimension. Science. 294: 1708-1712, 2001.

Pankov, R., Cukierman, E., Katz, B.-Z., Matsumoto, K., Lin, D. C., Lin, S., Hahn, C., and Yamada, K. M. Integrin dynamics and matrix assembly: Tensin-dependent translocation of [alpha]5[beta]1 integrins promotes early fibronectin fibrillogenesis. J. Cell Biol. 148: 1075-1090, 2000.

Cukierman, E., Huber, I., Rotman, M., and Cassel, D. The ARF GTPase activating protein: Zinc finger motif and Golgi complex localization. Science. 270: 1999-2001, 1995.

Complete List of Publications