Elizabeth Petri Henske, MD

Member
Medical Science Division


Elizabeth.Henske@fccc.edu
Phone: 215-728-2428
Elizabeth Petri Henske, MD


Recent Publications

2007

Robb, V.A., Karbowniczek, M., Klein-Szanto, A.J., Henske, E.P.  Activation of the mTOR signaling pathway in renal clear cell carcinomas.  J. Urol. 177:346-352, 2007.

2006

Henske, E.P.  Tuberous sclerosis complex.  In Encyclopedia of Respiratory Medicine, G.J. Laurent and S.D. Shapiro, Editors, pp 303–307, Elsevier Ltd., 2006

Crino, P.B., Nathanson, K.L., and Henske, E.P.  The Tuberous Sclerosis Complex. N. Engl. J. Med. 355:1345-1356, 2006. 

Astrinidis, A., Senapedis, W., Henske, E.P.  Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 (PLK1) in a phosphorylation-dependent manner. Hum. Mol. Genet. 15:287-297, 2006.

Robb, V.A., Astrinidis, A., Henske, E.P.  Frequent hyperphosphorylation of ribosomal protein S6 in lymphangioleiomyomatosis-associated angiomyolipomas.  Mod. Pathol. 19:839-846, 2006.

Karbowniczek, M., Robertson, G.P., Henske, E.P.  Rheb inhibits C-Raf activity and B-Raf/C-Raf heterodimerization.  J. Biol. Chem. 281:25447-25456, 2006.

Yu, J., Henske, E.P.  Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain.  Cancer Res. 66:9461-9466, 2006.

Astrinidis, A., Henske, E.P.  Mutation detection in tumor suppressor genes using archival tissue specimens.  Methods Mol. Med. 126:185-196, 2006.

2005

van, Slegtenhorst, M., Mustafa, A., Henske, E.P. Pas1 a G1 cyclin regulates amino acid uptake and rescues a delay in G1 arrest in Tsc1 and Tsc2 mutants in Schizosaccharomyces pombe. Hum. Mol. Genet. 14:2851-8, 2005.

Astrinidis, A., Henske, E.P.  Tuberous sclerosis complex: linking growth and energy signaling pathways with human disease.  Oncogene 24:7475-7481, 2005.

Karbowniczek, M., Henske, E.P.  The role of tuberin in cellular differentiation: are B-raf and MAPK involved? Ann. NY Acad. Sci. 1059:168-173, 2005.

Henske, E.P.  Tuberous sclerosis and the kidney:  from epithelium to mesenchyme, and beyond.  Pediatr. Nephrol. 20:854-7, 2005.

Neumann, H.P.H., Henske, E.P., Iliopoulos, O., and Glaesker, S.  Renal Involvement in Tuberous Sclerosis Complex and von Hippel Lindau Disease.  In Oxford Textbook of Clinical Nephrology, 3rd Edition.  A Davison, S Cameron, JP Grunfeld, C Ponticelli, C VanYpersele, and C Winearls Editors. Oxford University Press, pp 2397-2406, 2005.

Smalley, S.L. and Henske, E.P.  Autism and Tuberous Sclerosis Complex.  In The Neurobiology of Autism, 2nd Edition, ML Bauman and TL Kemper, Editors. The Johns Hopkins University Press, pp 265-275, 2005.

  

2004

Yu, J., Astrinidis, A., Howard, S., Henske, E.P. Estradiol and tamoxifen stimulate lymphangiomyomatosis-associated angiomyolipoma cell growth and activate both genomic and nongenomic signaling pathways.  Am. J. Physiol. Lung Cell. Mol. Physiol. 286:694-700, 2004.

van Slegtenhorst, M., Carr, E., Stoyanova, R., Kruger, W., Henske, E.P.  Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe. J. Biol. Chem. 279:12706-12713, 2004.

Karbowniczek, M., Cash, T., Cheung, M., Robertson, G.P., Astrinidis, A., Henske, E.P.  Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent. J. Biol. Chem. 279:29930-29937, 2004.

Astrinidis, A. and Henske, E.P.  Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex.   J. Child Neurol. 19:710-715, 2004.

Tazelaar, H., Henske, E.P., Manabe, T., and Travis, W.D.  Lymphangioleiomyomatosis.  In World Health Organization Classification of Tumours, Volume 5: Pathology and Genetics; Tumours of the Lung, Pleura, Thymus, and Heart.  WD Travis, E Brambilla, H Muller-Hermelink, and CC Harris, Editors.  IARC Press, pp. 107-8, 2004.

Stoyanova, R.S., Clapper, M.L., Bellacosa, A., Henske, E.P., Testa, J.R., Ross, E.A., Yeung, A.T., Nicolas, E.,  Tsichlis, N.,  Li, Y-S., Linehan, W.M., Howard, S., Campbell, K.S., Godwin, A.K., Boman, B.M., Crowell, J.A., Kopelovich, L., and Knudson, A.G.  Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations.  Cancer Biol. Ther. 3:1313-21, 2004.

 

Stoyanova, R., Upson, J.J. Patriotis, C., Ross, E.A., Henske, E.P., Datta, K., Boman ,B., Clapper, M.L., Knudson, A.G., and Bellacosa, A.  Use of RNA amplification in the optimal characterization of global gene expression using cDNA microarrays.  J. Cell Physiol. 201:359-65, 2004.