Samuel Litwin, PhD

Member
Population Science Division


Samuel.Litwin@fccc.edu
Phone: 215-728-2724
Samuel Litwin, PhD


Recent Publications

In Press

Litwin, S., Wong, Y-N., Hudes, G. Early stopping designs based on progression free survival at an early time point in the initial cohort. Stat. Med. (in press).

Myers, M.O., Meszoely, I.M., Hoffman, J.P., Watson, J.C., Ross, E., Eisenberg, B.L. Is reporting of recurrence data important in pancreatic cancer? Ann. Surg. Oncol. (in press).

Querec, T.D., Stoyanova, R., Ross, E., Patriotis, C. A novel approach for increasing sensitivity and correcting saturation artifacts of radioactively labeled cDNA arrays. Bioinformatics (in press).

Stoyanova, R., Querec, T.D., Brown, T.R., Patriotis, C. Normalization of DNA arrays by principal component analysis. Bioinformatics (in press).

2006

Summers, J., Litwin, S.  Examining the theory of error catastrophe.  J. Virol. 80:20-26, 2006.

2005

Litwin, S., Toll, E., Jilbert, A.R., Mason, W.S.  The competing roles of virus replication and hepatocyte death rates in the emergence of drug-resistant mutants:  Theoretical considerations.  J. Clin. Virol. 35:S96-S107, 2005.

2004


Movsas, B., Hudes, R.S., Schol, J., Millenson, M., Rosvold, E., Nicolaou, N., Litwin, S., Wang, H., Keenan, E., Curran, W.J.,Jr. Induction and concurrent paclitaxel/carboplatin every 3 weeks with thoracic radiotherapy in locally advanced non-small-cell lung cancer: An interim report. Clin. Lung Cancer (in press).

Xu, M., Floyd, H.S., Greth, S.M., Chang, W.C., Lohman, K., Stoyanova, R., Kucera, G.L., Kute, T.M., Willingham, M.C., Miller, M.S. Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects. Toxicol. Appl. Pharmacol. 195(2):232-246, 2004.

2003


Haas, N.B., Giantonio, B.J., Litwin, S., Minniti, C.J. Jr., Fox, S., Yeslow, G., Reilly, R., Nahum, K., Greenberg, R., Halbherr, T., Hudes, G.R. Vinblastine and estramustine phosphate in metastatic renal cell carcinoma. Cancer 98:1837-1841, 2003.

Masny, A., Daly, M., Ross, E., Balshem, A., Gillespie, D., Weil, S. A training course for oncology nurses in familial cancer risk assessment: Evaluation of knowledge and practice. J. Cancer Educ. 18:20-25, 2003.

Stoyanova, R., Upson, J.J., Patriotis, C., Ross, E.A., Henske, E.P., Datta, K., Boman, B., Clapper, M.L., Knudson, A.G., Bellacosa, A. Use of RNA amplification in the optimal characterization of global gene expression using cDNA microarrays. J. Cell. Physiol. 2003. DOI-10:1002-JCP.20074

Summers, J., Jilbert, A.R., Yang, W., Aldrich, C.E., Saputelli, J., Litwin, S., Toll, E., Mason, W.S. Hepatocyte turnover during resolution of a transient hepadnaviral infection. Proc. Natl. Acad. Sci. USA 100:11652-11659, 2003.

Upson, J.J., Stoyanova, R., Cooper, H.C., Patriotis, C., Ross, E.A., Boman, B., Clapper, M.L., Knudson, A.G., Bellacosa, A. Optimized procedures for microarray analysis of histological specimens processed by laser capture microdissection. J. Cell. Physiol. 2003. DOI-10:1002-JCP.20073

Zhang, Y.Y., Zhang, B.H., Theeli, D., Litwin, S., Toll, E., Summers, J. Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver. Proc. Natl. Acad. Sci. USA 100:12372-12377, 2003.

2002


Arnoletti, J.P., Hoffman, J.P., Ross, E.A., Kagan, S.A., Meropol, N., Freedman, G., Eisenberg, B. Preoperative chemoradiation in the management of adenocarcinoma of the body of the pancreas. Am. Surg. 68:330-336, 2002.

Cornfeld, M.J., Schnoll, R.A., Higman, S., Babb, J.S., Miller, S., Henigan-Peel, T., Balshem, A., Slater, E., Ross, E., Siemers, S., Montgomery, S., Malstrom, M., Hunt, P., Boyd, S., Engstrom, P.F. Implementation of a Comprehensive Cancer Control Program at the Worksite-Year One Summary Report. J. Occup. Environ. Med. 44(5):398-406, 2002.

Evans, A.A., Chen, G., Ross, E.A., Shen, F.M., Lin, W.Y., London, W.T. Eight year follow-up of the 90,000 person Haimen City Cohort: I. Hepatocellular carcinoma mortality, risk factors, and gender differences. Cancer Epidemiol. Biomark. Prev. 11:369-376, 2002.

Lewis, N.L., Scher, R., Gallo, J.M., Engstrom, P.F., Szarka, C.E., Litwin, S., Adams, A.L., Kilpartick, D., Brady, D., Weiner, L.M., Meropol, N.J. Phase I and pharmacokinetic study of irinotecan in combination with raltitrexed. Cancer Chemother. Pharmacol. 50:257-265, 2002.

Mason, W.S., Litwin, S.  Pathogenesis of hepadnavirus infections.  In:  Hepatitis B Virus, eds. Lai, C., Locarnini, S.  International Medical Press, Chapter 7, pps. 99-111, 2002.

Pingpang, J.F., Hoffman, J.P., Sigurdson, E.R., Ross, E., Sasson, A.R., Eisenberg, B.L. Pancreatic resection for locally advanced primary and metastatic nonpancreatic neoplasms. Am. Surg. 68:337-341, 2002.

Sasson, A.R., Hoffman, J.P., Ross, E., Kagan, S., Pingpank, J.F., Eisenberg, B.L. En bloc resection for locally advanced cancer of the pancreas: Is it worthwhile? J. Gastrointest. Surg. 6:147-158, 2002.

Sauter, E.R., Chervoneva, I., Diamandis, A., Khosravi, J.M., Litwin, S., Diamandis, E.P. Prostate-specific antigen and insulin-like growth factor binding protein-3 in nipple aspirate fluid are associated with breast cancer. Cancer Detect. Prev. 26(2):149-157, 2002.

Sauter, E.R., Takemoto, R., Litwin, S., Herlyn, M. p53 alone or in combination with antisense cyclin D1 induces apoptosis and reduces tumor size in human melanoma. Cancer Gene Therapy 9:807-812, 2002.

Sauter, E.R., Yeo, U.C., Von Stemm, A., Zhu, W., Litwin, S., Tichansky, D.S., Pistritto, G., Nesbit, M., Pinkel, D., Herlyn, M., Bastian, B.C. Cyclin d1 is a candidate oncogene in cutaneous melanoma. Cancer Res. 62(11):3200-3206, 2002.

Yamamoto, T., Litwin, S., Zhou T., Zhu, Y., Condreay, L., Furman, P., Mason, W.S. Mutations of the woodchuck hepatitis virus polymerase gene that confer resistance to lamivudine and 2'-fluoro-5methyl-b-L-Arbinofuranosyluracil. J. Virol. 76(3):1213-1223, 2002.

2001


Cornfeld, M., Miller, S., Ross, E., Schneider, D. Accuracy of cancer-risk assessment in primary care practice. J. Cancer Educ. 16:193-198, 2001.

Daniel, R., Litwin, S., Katz, R.A., Skalka, A.M. Computational analysis of retrovirus-induced scid cell death. J. Virol. 75(7):3121-3128, 2001.

Ochs, M.F., Stoyanova, R., Brown, T.R., Rooney, W.D., Springer, C.S. A Bayesian Markov Chain Monte Carlo solution of the bilinear problem. In Bayesian Interference and Maximum Entropy Methods in Science and Engineering, edited by J.T. Rychert, G.J. Erikson, C.R. Smith. AIP Conference Proceedings, Melville, New York, Vol. 567, 2001.

Pei, J., Balsara, B.R., Li, W., Litwin, S., Gabrielson, E., Feder, M., Jen, J., Testa, J.R. Genomic imbalances in human lung adenocarcinomas and squamous cell carcinomas. Genes Chromosomes Cancer 31(3):282-287, 2001.

Stewart, J.J., Watts, P., Litwin, S. An algorithm for mapping positively selected members of quasispecies-type viruses. BMC Bioinformatics 2(1):1, 2001.

Pingpank, J.F., Hoffman, J.P., Ross, E.A., Cooper, H.S., Meropol, N.J., Freedman, G., Pinover, W.H., LeVoyer, T.E., Sasson, A.R., Eisenberg, B.L. Effect of preoperative chemoradiotherapy on surgical margin status of resected adenocarcinoma of the head of the pancreas. J. Gastrointest. Surg. 5:121-130, 2001.

Sasson, A.R., Hoffman, J.P., Ross, E., Meropol, N.J., Szarka, C.E., Freedman, G., Pinover, W., Pingpank, J.F., Eisenberg, B.L. Trimodality therapy for advanced gallbladder cancer. Am. Surg. 67:277-284, 2001.

Stoyanova, R., Brown, T.R. NMR spectral quantitation by principal-component analysis. NMR Biomed. 14:271:277, 2001.

Szarka, C.E., Yao, K.-S., Pfeiffer, G.R., Balshem, A.M., Litwin, S., Frucht, H., Goosenberg, E.B., Engstrom, P.F., Clapper, M.L., O'Dwyer, P. Chronic dosing of oltipraz in people at increased risk for colorectal cancer. Cancer Detect. Prev. 25(4):352-361, 2001.

Zhu, Y., Yamamoto, T., Cullen, J., Saputelli, J., Aldrich, C.E., Miller, D.S., Litwin, S., Furman, A.P., Jilbert, A.R., Mason, W.S. Kinetics of hepadnavirus loss from the liver during inhibition of viral DNA synthesis. J. Virol. 75:311-322, 2001.